More often than not, valuable discoveries are simply used to create new patentable drugs. Meanwhile, natural products that can solve the problem without any side effects are blatantly ignored.
Here’s a perfect example. Scientists have confirmed that a group of immune system proteins, known as RANK L, activate immune cells and convert them into osteoclasts – cells that remove bone. This discovery has brought about the relatively new osteoporosis drug Prolia (denosumab), a twice yearly injectable drug that blocks the effects of RANK L. Prolia has its own list of nasty and sometimes dangerous side effects, so if you haven’t yet, I urge you to read ‘Prolia (Denosumab): My Review’ to get all the details.
Complicate… Then Medicate
RANK L is also switched “on” by inflammatory cytokines, including IL-6 which is abundant in patients with Rheumatoid Arthritis. It causes bone loss in RA patients and it is often also present in healthy individuals, accelerating bone loss which can lead to osteoporosis. IL-6 shares a binding site with RANK L, so when IL-6 is activated, so is RANK L.1
On the surface and without taking into account its side effects, Prolia could sound like a logical solution to bone-damaging inflammation and osteoclast activation.
But what if I told you that long before Prolia was invented, researchers at the Department of Experimental Medicine and Oncology at the University of Turin in Italy have shown that RANK L could be appropriately moderated by simply taking Omega-3 supplements?2 Did the medical establishment “forget” about this study? The answer is quite obvious, I think… Omega-3 fatty acids cannot be patented.
Omega-3: Better Than Osteoporosis Drugs!
If you have the Save Our Bones Program, you know that in it I explain that Omega-3 fatty acids increase calcium and Vitamin D absorption and prevent excessive bone turnover, thus helping reduce bone loss.
I also write that Omega-3 is an excellent natural anti-inflammatory. Most Omega-3 supplements are made with fish oil, and I in the Program I warn of potential contaminants and toxins.
Till next time,
1 Matsusaka T et al. “Transcription factors NF-IL6 and NF-kappa B synergistically activate transcription of the inflammatory cytoknes, interleukin 6 and interleukin 8.” Proceeding of National Academy of Science, Vol. 90, pp. 10193- 10197, Nov. 1993.
2 Camandola S. et al. “Nuclear factor kB is activated by arachidonic acid but not by eicosapentaenoic acid.” Biochem Biophys Res Commun. 13;229(2):643-7. Dec. 1996.
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