This past June 1st, the FDA approved Prolia ™ (denosumab), a brand new twice-yearly injectable osteoporosis drug by Amgen.
The first drug of its kind, Prolia was designed to treat and prevent postmenopausal osteoporosis for patients considered to be at high risk of fractures. It’s also marketed as an alternative treatment for those who have failed or are intolerant to other osteoporosis drugs.
Is this a time to celebrate, or is Prolia destined to end up in the osteoporosis “Hall of Shame”, along with the rest of Big Pharma’s Superstar osteoporosis drugs? I’ll let you decide, but first, let’s unravel the mysterious and tightly-woven cocoon wrapped around this novel drug.
An Old and Flawed Concept Disguised as Sci-Fi Technology
As if straight out of a sci-fi movie, the Space Agency NASA was involved in several studies related to Prolia. Here’s the scoop: in 2001, Ted Bateman, Ph.D. from Clemson University in South Carolina and Paul Kostenuik, a researcher for Amgen, teamed up to “…use the microgravity environment for evaluation of new pharmaceutical candidates (denosumab) in small mammals. Results may expedite the review of new pharmaceuticals.”1
They conducted studies on 24 female mice that spent 12 days on the International Space Station shuttle flight STS-108. Study findings confirmed that Prolia did prevent increased bone loss and maintained bone mineralization. So there you have it. The medical establishment is more than willing to send mice to space – but would they consider a natural, safe, and easy treatment? Out of the question!
On the surface, Prolia seems to be a breakthrough and fairly innocuous drug. But is it? As the first fully human monoclonal (laboratory-made) antibody and RANK Ligand inhibitor to be approved as a drug, it certainly sounds very complicated. But it really isn’t. Bear with me… I’ll explain.
Antibodies are proteins produced to neutralize “invaders”, such as bacteria and viruses. RANK Ligand (RANKL for short) is a protein that activates osteoclasts and is involved in immune-response regulation.2 As I explain in the Osteoporosis Reversal Program, osteoclasts are bone cells that remove old bone by a process called resorption. They make space so that new bone is deposited by osteoblasts, thus replacing old bone. These two processes are known as bone remodeling, the natural way by which bones renew themselves and stay strong, healthy, and more resistant to fracture.
Prolia: Same as Bisphosphonates… Only Different
Now back to Prolia. The natural inhibitor of RANKL is osteoprotegerin, a tumor necrosis factor (TNF) cytokine that binds to RANKL, preventing interaction with its receptor-activator RANK on the surface of osteoclasts.3 Cytokines are chemical messengers that help regulate the nature and intensity of an immune response. Remember this for later, because it all ties in together.
So, in plain English, Prolia mimics osteoprotegerin by blocking the effects of RANKL and de-activating osteoclasts. Say “hello” to stalled bone resorption and “good-bye” to new bone deposition. But wait a minute, doesn’t this sound eerily familiar? It should, because bisphosphonates achieve the same end result as Prolia, only through a different biochemical pathway.
At the end of the day, both drugs alter normal bone metabolism, not without potential long-term nefarious consequences. For example, sudden femoral fractures are linked to long-term bisphosphonate therapy, which can be attributed to the lack of bone remodeling. Add to this formula a dose of immune system tampering, and you’ve got yourself a fully assembled health Molotov cocktail.
Studies and Stats
Amgen’s own Press Release states that “Treatment with Prolia resulted in greater bone density, stronger bones, and reduced risk for vertebral, hip and non-vertebral fractures measured at three years.”4 It backs up this statement with a study by Cummings et al. published by the New England Journal of Medicine in 2009, titled “Denosumab for Prevention of Fractures in Postmenopausal Women with Osteoporosis”.
And the same Press Release boasts their pivotal three year Fracture REduction Evaluation of Denosumab in Osteoporosis every six Months or “FREEDOM” study (no, this is not a bad joke) with these results:
– 4.8 percent absolute risk reduction of vertebral fractures - 0.3 percent absolute risk reduction of hip fractures - 1.5 percent absolute risk reduction of non-vertebral fractures - 8.8 percent bone density increase at the lumbar spine, 6.4 percent at the total hip, and 5.2 percent at the femoral neck.
So far, so good, especially for those who don’t mind being “guinea pigs” in exchange for short-term rewards. Because the biggest cause for concern with Prolia is its potential side-effects.
A Wolf in Sheep’s Clothing
Even though Prolia doesn’t accumulate in the body and has no known esophageal side effects as is the case with bisphosphonates, it boasts a rather long list of undesirable – and sometimes dangerous – potential side effects. In its shadow, bisphosphonates almost seem to be the lesser of both evils, and that’s no small feat. You’ll soon know why.
The most common side effects of Prolia are back pain, arm and leg aches, elevated cholesterol, general musculoskeletal pain, bladder infection, and pancreatitis.5
And as disclosed on the Prolia website (https://www.prolia.com), it can cause serious side effects because it “is a medicine that may affect your immune system” (remember the cytokines?).
These are the main side effects listed by Amgen:
- Low calcium levels
- Serious skin, lower abdomen, bladder, or ear infections
- Dermatitis, rash, or eczema
- Inflammation of the inner lining of the heart (endocarditis) caused by an infection
- Severe jaw bone problems such as osteonecrosis of the jaw.
And for dessert, Amgen serves up a cautionary statement: that “it is not known if the use of Prolia over a long period of time may cause slow healing of broken bones or unusual fractures.”
So it looks as though…
The More Things Change, the More they Stay the Same
Like bisphosphonates, Prolia opens the door to a wide array of opportunistic health problems, many of which can (and trust me, will) get covered over with yet more drugs.
And let’s not forget that this drug interferes with the body’s natural immune system, which is the obvious reason for many of its most dreaded side-effects. In fact, roughly one year before its approval, FDA reviewers expressed concerns over Prolia’s activity against an important immune system modulator.6
But evidently, those concerns were shoved to the side and quickly forgotten. It seems as though the medical establishment considers drug side-effects – no matter how terrifying – an unfortunate “numbers game”. Applying its skewed logic, it accepts that there will always be some unlucky patients that will get stuck with irreversible damage, such as osteonecrosis or endocarditis – the latter potentially resulting in heart valve destruction or even a stroke.7 The unsuspecting victims are written off as inevitable casualties of war, losing their battle, but helping win the war against “disease”.
Don’t Get Fooled by Confusing Double-Speak
It almost seems as though well-meaning scientists focus so disproportionately on solving bone health issues using hi-tech tools, that they lose sight of the risk vs. reward ratio. That’s why together at Save Our Bones, we expose the truth and dispel misconceptions, especially as they relate to brand new drugs.
Let’s face it: two injections a year may sound like an appealing solution to finally conquer osteoporosis. But the bad news is the potential high price to pay. So I urge you to consider your acceptable options and weigh the consequences of your decision. Also, please share this review with anyone you think may benefit from it.
And ALWAYS remember the good news: the Save Our Bones community is here for you and your bone health, with proven natural bone health strategies that work with your body… not against it.
References
1 Commercial Biomedical Testing Module: Effects of Osteoprotegerin on Bone Maintenance in Microgravity (CBTM). https://www.nasa.gov/mission_pages/station/science/experiments/CBTM.html].
2 Lacey DL, Timms E, Tan HL, Kelley MJ, Dunstan CR, Burgess T, Elliott R, Colombero A, Elliott G, Scully S, Hsu H, Sullivan J, Hawkins N, Davy E, Capparelli C, Eli A, Qian YX, Kaufman S, Sarosi I, Shalhoub V, Senaldi G, Guo J, Delaney J, Boyle WJ . Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell. 93:165–176. 1998.
3 Nakagawa N, Kinosaki M, Yamaguchi K, Shima N, Yasuda H, Yano K, Morinaga T, Higashio K. RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis. Biochemical and Biophysical Research Communications. 253:395–400. 1998.
4 https://wwwext.amgen.com/media/media_pr_detail.jsp?releaseID=1433162
5 https://www.centerwatch.com/drug-information/fda-approvals/drug-details.aspx?DrugID=1104
6 https://www.medpagetoday.com/ProductAlert/Prescriptions/15486
7 https://www.nlm.nih.gov/medlineplus/ency/article/001098.htm
Would appreciate comments on Strontium ranelate.
Just had a dexa scan after 12 months of SR and bone supplementS plus attention to diet. Scan was up 7.55
Hi Ann – I wrote a whole section about strontium ranelate and Protelos in my handbook, “The Natural Bone Building Handbook,” which you can download for free by filling in the form on my home page at https://saveourbones.com. And nice job on the dexa scan! Keep up the good work!
Vivian, thanks for providing all the “heads up” email. I hope you don’t feel too bruised as I have tossed you around to a lot of my friends who can benefit from your info. Sorry I can’t loan out my book as I am constantly referring to it but I’m encouraging my friends to get on the band wagon. And as for the future…I already see a large trend of women taking charge of their health, via a broader information source and relying on a more natural way to keep their bodies healthy and resolve issues in a more natural way. Keep up the great work…
That kind of bruising I can handle. Thanks for the positive words. And you’re absolutely right – we’re part of a growing revolution. The truth is a powerful force.
Haven’t checked on prices but is Prolia and Reclast as expensive as Forteo?
Hi Janie,
I’m sure you can get this information online or from a pharmacy. I don’t keep track of drug prices.
vivian,
my friend had her first prolia injection today. she said it was $800. she had a headache and said it felt like a very strong man punched her in the arm. she has taken boniva for a couple years but it didnt help her. she has had some issues that appeared to be cardiac related but as far as i know, has no concrete diagnosis. as i think back, at least one of these episodes occurred while she was taking boniva. she seemed so excited about this new injection, in spite of the current symptoms.
i read many alternative sites and choose nutrition and vitamins, etc over any drugs- i search out everything. i care for this person and want to share this info with her. how is the best way to introduce some truth to someone, who is clearly concerned with the situation without sounding condescending of the choices she has made or like i am somehow smarter than she. so many people think the dr. is a god, only looking out for your good, receiving no monetary reward for the suggestions they give. it’s so frustrating that people dont research these things for themselves! i truly want to inform those i am in contact with out of love but people look at you like you are freakin’ crazy for not believing MD’s, FDA, drug companies, etc. and embracing healthy, God-given alternatives. seems to me, the more tests they come up with, the more “diagnoses” they come up with, the more drugs are pushed, the sicker people get. why dont people see this???? heaven help us!
{ i must give appreciation to my GP who really listens to me. one who cares about the things i’ve read, who doesnt push meds on my family, who prefers nutrition and exercise and gives you choices. ie: he prescribed melatonin for an unusual insomnia episode i had. after 2 weeks on 2-3 hours sleep, he reluctantly gave me ambien for a couple weeks. i wish more drs were like him and my chiropractor.}
thank you for informing people!
Dear Friend, Vivian,
Thank you yet again for your good work and for revealing this latest “medicine” Prolia, for osteoporosis. I am so glad that you are around to do the impossible (for us) research on the latest fraud. We appreciate everything you do.
F. Brandwein
Thank you very much for all your information Vivian.
I do not take any prescription drugs. Am 76 but take 28 vitamins and minerals daily.
Cured myself of RA after getting it from allergy shots in the 60’s.
I also exercise daily 1 1/2 hours when I don’t golf or bowl.
After
That’s fantastic, Joan! Congratulations on taking charge of your health.
Just curious how you cured yourself of Rheumatoid Arthritis. I have a similar form or arthritis, and also osteoporosis from taking methylprednisolone for 9 years. Any advice would be appreciated.
The goal of drugs companies is to make money not to cure people, its that simple. We will see
more drugs in the market in the future because people buy them. For me the best alternative is the natural way, like many years ago where all these drugs didn’t exist. Now that we have them we see thar they make moredamage than good
On the advice of her Dr.my 91 year old mother took the Prolia injection. Two months later she was in the hospital. She was in p
perfect health until taking the injection. She had a bleeding ulcer ,bla
blader infection,fluid on the heart and irregular heart beat. She spent a week and half at the hospital. They say report in serious side effects but they do nothing about them. When you have the side effects it is too late. Do not take the shot
I have been reading all these comments on prolia and am confused I dont want any painful side effects . Considering not taking it
Wow…you all should take a look at the insurance companies, they make A LOT of money and most of the time they are the ones that determine the drugs that you all take.
How many times have you been given a prescription from your doctors and when you get to the pharmacy they either change it with out asking you or they tell you that you can get a generic or something different at a cheaper price?? You should write a blog about the insurance companies and stop complained about the drug companies.
And there are so many scientist out there trying to save people from cancer, alzheimers, and so many other diseases and most of this research is actually paid for by pharmaceutical companies. Good companies actually use some of the money you pay for your drugs to do reaseach and develope new products to help people live better lives.
Also, try reading the patient information on the back of all your products and you will see side effects for everything, for your tums, advil, etc… The FDA makes these companies write everything and anything in this product information. Advice to you all would be to look at numbers…was it 90% of patients that had a side effect or 0.05% of patients. Did 50 people in a study of 8,000 have a side effect or was it 50 people in an 800 person study????
Don’t believe everything you read, especially on these internet websites…DO YOUR HOMEWORK ask more than one doctor, look things up in medical journals if you are that concerned not online.
Irma…what you say doesn’t make sense. Every industry or business has to make money to survive. Pharma companies create great and sometimes not so great drugs. It’s in their best interest to have the best drug out there..so that they can be the leader in the market…and utimately make even more money where they will further invest into developing more life saving treatments. Any doctor or pharmaceutical company would love to receive the accalades of being the maker of revolutionary treatment. Remember its researchers/doctors who create the drug – they wouldn’t be able to do this if not for the funding that comes from big pharma!
Thank you ! I look forward to and appreciate your hard work on our behalf. Keep up the good work.
Thank you so much, Vivian, for keeping us well informed.
I enjoy all the practical information, and Vivians knowledge of all the drugs. We seem to so easily accept what ever Doctors want to slip into us but I for one have learned to say no! Thanks Vivian.
Bonnie from Ontario CA
Vivian: I have felt so much better since I have been off Fosomax and then Boniva. It is a pleasure to be able to raise my arms and do things I couldn’t do before because of pain.
I appreciate your study and comments and the latest with this new drug and I assure you, it will not be part of my diet. Thank you very much.
dear Vivian- this is jeanne arden – did I remember t o tell you I am 86yrs. of age. I rec’vd an e-mail from Michael and want to thank you for allowing me to order it seperately. My check will go out in the mail on Monday. I am on the west coast of Fla., near theTampa-St. Pete area. Lov your info. affectionately, Jeanne
Interesting. Current issue of WORST PILLS, BEST PILLS NEWS had an article on bisphosphonates and NSAIDs. Says that there is evidence that people who ingest both have an increased risk of gastrointestinal ulcers. It also says that there is an increased risk when taken separately. The more pills we take, the sicker we get!
Morning Vivian thank you for all your information on our bones , i all ways pass it on to my sisrerinlaw in England, yours Maggie Loftus Kitimat B C
I have been diagnosed with osteoporosis in my spine, and have a wedge fracture at T10.
I have resisted taking any medication but I have a very healthy vegetarian diet, do yoga twice a week and have acupuncture.
I also take supplements of garlic, glucosamine, flax oil,calcium, magnesium and vitamin D3.
I have heard about strontium which builds bone and is recommended by the British Osteoporosis Society, but according to NICE guidelines, my doctor cannot prescribe it unless I have tried the other meds on offer, which I don’t want.
Any advice?
Hi Jane,
I can’t address the protocols your doctor follows, but before taking strontium, you might take this information into account.
Only minute amounts of strontium belong in the bones. Strontium does increase density and both trabecular and cortical strength, therefore making bones denser and thicker. However, thicker and more densely packed bones lack ductility and tensile strength. Tensile strength is the ability of bones to resist stretching or pulling. Fractures involve tensile strength and compressive strength as well. Strontium hardens bones unnaturally and alters their tensile strength, actually making them more prone to fracture. Also, strontium is denser than calcium and gives false bone density test results. Some suggest reducing T-score numbers by 20% when taking strontium because of that.
i read recently on NOF that strontium is being associated with hair loss – alopecia in some people….so another good reason not to take it..who wants to be bald??? I had a wig once and it kept slipping off my head…thanks I will keep my own hair!
Do the drug Companies only know how to stabilise an ailment,because if they know this then why don’t they cure wth the same knowledge? I wonder why?
Since 2005 my bone density numbers continued to go down. I had been taking Evista for a long time. Can’t remember when I started. I stopped taking Evista over a year ago. I exercise 6-7 hours per week. In January of 2010, my bone density numbers went up slightly. I was elated since the exercise started only a few months before that. My Dr. wanted me to continue the drug. I refused. He said that if I took the bone density test again on the same day, it my be different numbers. What does that tell you? He also mentioned that the drug prevents breast cancer. Well, how can one drug be curer of two conditions ???? No thank you. I will continue my current program of exercise and diet. Thank you Vivian for all your information.
After all the sick days I spent when I took those awful phosphate things I don’t feel like trying another. I was going to take Aclastic (or whatever it is called) and then heard from a woman who had terrible jaw problema and has never gotten rid of them. Guess I’ll just try to eat right, stay healthy and maybe I’ll be lucky enough to live till my 82nd birthday in December. What more can I ask. Thank you Vivian. Think I’ll stay on your side!!!! Avis
Iam 55 and diagnosed with ostepenia a year ago. recent dexascan showed bone mass stayed the same. My scores areapspine L1-L4 t score -1.4 z-score-0.4. duel Femur Neck Mean t score-2,0 t score -0.7 and duel femur-l.7 z score -0.7 what should I be doing have been on HRT bioidentical cream for about a year what do you suggest
Denise, I don’t recommend any type of Hormone Therapy. If you haven’t already, I suggest you check out the free The Natural Bone Building Handbook – I’m confident you’ll benefit from it.
Hi Vivian…
Was just thinking about all the tests they give to the lab animals. If we had them, we would complain and tell them we hurt, etc.
If any of the animals have side effects, how would they know about them? Animals do not talk or complain… How can they say that these are true tests???
Elizabeth W.
Dear,Vivian,I’m sorry I don’t always comment,but your emails are always much appreciated.Thank you.Vivian,for the useful info on Prolia. Best wishes.Elzbieta.
Thanks for the heads-up on Prolia. As someone with low immune levels, I definitely will steer clear of something that might further compromise my immune system. I’m fed up with doctors who prescribe without looking at the med history of their patients. Your information cuts through the pharmajargon.
I have a question for you in connection with teva-alendronate lendronate sodium. Have you ever heard of it having negative effects on scoliosis?? Could you let me know? Thank you.
Grace.
Dear Vivian, what is your opinion on “MCHC” – supposedly a form of calcium. Thank you!
Vivian
I am a NP in a large primary care office in ND and also an Osteoporosis pattient since I was 29. I was involved in the clinical trials for Denosomab, as both an investigator and a patient. I have read your emails for the past few years and agreed with you most of the time, but I have to tell you that I feel you did not do your homework on Denosomab/Prolia.
I was also involved with clinical trials of most of the major oral BP’s, and I can attest first-hand that Denosomab is an excellent alternative that is both safer and more effective than any other treatment options currently on the market.
In your review you wrote that Prolia’s most common side-effects were: back pain, arm and leg aches, elevated cholesterol, general musculoskeletal pain, bladder infection, and pancreatitis.5
But if you check their package insert data from their pivotal clinical trial, you will find that all of the above were equally balanced in the placebo group (eg 1307 patients had back pain on Prolia, and 1301 had back pain on placebo). To me and most clinicians, that means there is no back pain related to Prolia. In fact there were no statistically significant side-effects found between Prolia and the placebo group in their trial which included 7,808 woman across the globe.
You also mentioned opportunistic infections, but the were actually more opportunistic infectios in the placebo group than in the Prolia group.
What impresses me most about this drug is its safety profile and its ability to decrease fractures, while also significantly increasing bone mineral density. I also put my mother on it as soon as it came out.
Again, I am a big fan of yours, but you really need to spend some time immersing yourself in the science and talking to people who have in-depth clinical knowledge of a biologic before you write a review.
Thanks
Tiffany
Thanks Tiffany for your information. Please keep us updated on your mother. Personally, I will avoid the drugs and follow Vivian’s advice. I realize that drugs are necessary sometimes, and I am thankful for the help they offer in those instance’s. But from my own personal experience and watching loved ones….I will avoid them like the plague as much as I can.
I appreciate your comments, Tiffany. However, regardless of the studies conducted against placebos, common sense dictates that there will be some unlucky “patients” that will suffer from bad side-effects caused by this new drug.
To me, each person counts…I don’t look at the whole group as a statistical calculation, as these “studies” do.
The bottom line is that there is no question that Prolia (denosumab) tampers with the body’s immune system and with bone remodeling. And it’s not as though there’s no other solution for bone loss…
Let this be clear: I look at our biology as a whole ecosystem. Mainstream science isolates one health problem and attempts to invent miracle drugs to unnaturally correct it, at the expense of other important biological functions.
i took foxamax 1 year, it destroyed my jaw i lost all my teeth and severe hypotention. occured
i took frteo i got naseated los sever amts weght my blood pressure is severely low,
then now i am on calcotonin-salmon, i am very dizzy, hard to walk wobbley feet, my blood pressure is severely low my sodium blood level is low and i a not getting better.
what about the new drug damamale? what are all the severe risks of these meds given for my severe low bone density? please mail me liturature on this
billie lee hamon mrs.
50417 irene street
box 121
cabazon. california 92230
Dear Vivian,After aterrible reaction to Boniva.I would never try any drug.Commonsense eating and Vitamin K2 have helped me.No more drugs.Janet
Thanks again Vivian, it is comforting to know that there is someone out there looking out for us.
Marg W.
Thank you, Vivian, for the information, for the scientific details, and for the simple explanations of them.
Shula
Very interesting information so I thank you Vivian.
I have been following your acid/alkeline diet for one year now and feel great. I have just had a physical and have found out that my B12 is low from eating 80/20. Is this common?
Low B12 levels are usually due to a lack of intrinsic factor or low stomach acid levels. I recommend a B-complex supplement.
Thank you for your information. I consider it very valuable, as I choose to stop the fosamax program and boniva….just three years and I had all the bad side effects…..Glad to be rid of the drugs. Am diligent with diet , weight work outs, and exercise, and supplements. Will nownext yeat if I am holding steady…
My mother has severe osteoperosis in the spine and back and the doctor has recommended a once yearly injection of Aclasta.What do you now about this product and is it any different than Prolia.
Aclasta, also known as Reclast (zoledronic acid) is an IV bisphosphonate.
I discuss it in the FREE Natural Bone Building Handbook.
I also go into it in greater detail and provide natural and effective alternatives in the Osteoporosis Reversal Program.
I was just wodering what your thoughts are on a condition that I have. I take 5mg. of prednisone daily for the past 4 years. What could I do naturally to help myself? I do not want to take any of the drugs the Drs. suggest.
Thanks for the update on the latest treatment for osteo. Your book and Dr. Fuhrman’s books have enabled me to be brave and say no to taking anymore osteo drugs. I was a guinea pig for Evista, Fosamax, and Reclast. The Reclast put me in bed for four days with severe pain throughout my body. My doctor said don’t worry there are other treatments like Forteo. That is when I stopped listening and changed my diet. I’m now a vegan & will never take those darn drugs again. Vivien thanks for your knowledge and spunk! It has helpe me to change my lifestyle. I am grateful. 🙂
Great article. That’s why, when my doctor asked why I won’t take any osteoporosis drugs to avoid fractures, I asked him if he pays attention to all the side effects listed in commercials and labels. No response to my question.
I think he got the picture.
Yep! Knowledge IS power…
Thanks for the continued e-mails and your tenacity in researching the drugs and their potential side effects. I am a 5 year breast cancer “survivor” so I have endured some of the nastiest drugs imaginable as well as radiation. I stopped taking Boniva after one year due to the awful side effects. Your diet and advice have made a huge difference physically and mentally. I thought it would be difficult and time consuming; it is NOT! I want to tell everyone how easy it is to be healthier and stronger without drugs. Please keep sending your e-mails.
vivian- well, i was just injectd with the new drug priloa and I guess I better hope or the best, Thanks for your update.
How do I get the Save Our Bones PROGRAM bOOK
Here you go, Katherine – Osteoporosis Reversal Program
Yes, Vivian, I do like all the inof. that is sent out. I read them all the time.
Thanks Steve.
thanks Vivian for all your good information there is one question i am curious about if fluoride hardens teeth why not bone as teeth,nails,hair, bone,ect are made up of the same components, it has always puzzled me. If you could answer this i would be very grateful.
Thanks again Rhonda
Hello Rhonda in Australia.
Your query concerning fluoride was a good one and encouraged me to do a little research.
Please note:
Save Our Bones”, Chapter 8, page 98 under ACTION.
Save Our Bones /Program Glossary page 10…
fluoride, fluorine and fluorosilicic acid.
Chapter 7, page 87 under Let’s summerize… “the key to prevent osteoporosis is to maintain body tissues in an alkaline state.”
Chapter 8, page 95 paragraph 1 .. “Chemicals, preservatives and drugs have a very strong acidifying effect on our tissues.”
Refer to https://en.wikipedia.org/wiki/Fluoride.
Notice “Applications”.
This has giving me better insight into the reason for avoiding fluoride. Hope it helps you, too.
Cora in Phoenix
Look what I found in researching your question.
Cora
https://www.health-science.com/fluoride_toxicity.html
Thanks for providing links to the flouride references in Osteoporosis Reversal Program, Cora!
Hi , very well, I really appreciate your articles: they are eye openers. I did not hear about this new drug Prolia, but to be honest I am not interested in anything that doctors prescribe for bone density, because i am sure that every drug out there has potentially harmful side effects . thank you anyway, its good to know.
josephine
Dear Vivian,I had a letter written here and it disappeared.Why do THEY think women are all stupid.?! This is a great email and I thank you for it and being in my corner. Mary
Dear Vivian,I’m sorry I don’t always comment,but your emails are always much appreciated.This one is exceptionally good.HOW DARE THEY? Do they consider all women stupid,I guess you’d better not answer that.
wonderful simple explanation of Prolia & exactly the reason I chose Forteo despite all its potential side affects, due to severe osteoporosis despite having followed the proper nutritional & supplemental alternatives since 1983. So with insurance paying the bill & my fear of more fractures and ending up living in my 17 year old car, after 2 years, I made this choice. Would love to read your chemical impression of Forteo. Don’t hesitate to mention “scary” side effects….I read them. Just curious on your input. Thanks Vivian !!!
Great reseach again. I have had signifigate gains in the bone scans in one year with NO DRUGS. I have taken a natural approach with Bio Idential Hormons. Holistic approach to eating. High quailty vitimans and supplements. Yoga and Pilates . My can a year ago was -4.7 for my spine I am now -4.1 and stronger fitter and feeling younger then I ever have. Vivan keep people on the right track and say NO to the drug companies.
I know how important exercise is, BUT have had four hip surgeries and can no longer hike, play tennis, etc. Do some non-impact BUT will that help?
From what I have read, both through Vivian’s book & research as well as elsewhere, low impact exercise is beneficial, particularly when it is weight-bearing. Free weights are considered better than resistance machines, but everything helps. It’s really important to get advice on doing the movements correctly to get the most benefit and avoid injury.
I believe that the best way to prevent/stop & or reverse osteoporosis
is to engage in a Proggresive Strength Training program.The safest
& most effective is a “Super Slow” or Low Velocity strengthening
method.If Vivian or anyone has questions they can contact me at
be*************@****om.Keep up the “good work”Vivian I am against
the use of alcohol & all drugs if not only for very rare instances of
life saving emergencies.Thanks Bert Vila Super Slow & Medx
certified.
Once again Vivian, thank you for the latest news. Sounds like this is another “innovation” for us to skip. As always I will pass on this information to all my tennis, golfing and tap dancing buddies. gerri
Please tell me about strontium renalate. just started it 1 1/2 months ago.
Thank you.
Sharon Leblang
ds*******@*ol.com
I discuss Strontium Ranelate in the Natural Bone Building Handbook.
I also go into it in greater detail and provide natural alternatives in the Osteoporosis Reversal Program.
We need answers.30 year old male is losing bone loss every second .He has lost 4 inches and is now in a wheel chair .Doctors are at a loss why he is losing bone loss and has many fractures so rapidly.Calcium is showing in his urine.Father of 3 and loving husband.Any help out there?
Check the thyroid and parathyroid. Also check the calcium in the blood. The parathyroids control the calcium. If they are out of whack, the calcium that is supposed to go to the bones goes into the blood and eventually ‘out’.
The only reason I know this is just had thyroid/parathyroid surgery. Calcium count pre-op (day of surgery) 66. Immediately following surgery 9.
Also, I have a rare ditty called Cowden’s Syndrome. The doctors have to look outside the book.
I wish you lots of luck.
Sandy
In my case, my parathyroid ended up being normal. They were convinced it was that, too, before testing. I had to go to multiple doctors and did not give up even after celiac test came back negative.
I just came from my endocrinologist who said the link to absorbing Calcium (my calcium has been high) is D which is necessary to absorb Calcium. I was also deficient in other vitamins, especially all B’s because of wheat and gluten intolerance confirmed by genetic testing (I had both genetic markers) not celiac test, which came back negative! This intolerance affects ability to absorb all nutrients and results in systemic inflammation. I have quit eating wheat and gluten which has pretty much put my auto-immune disorder in remission. I have to take more readily available vitamin supplements but at least my body is now able to D, B’s, etc. Hope this helps your situation.
Hello!
I was dx.woth osteopenia in my spine and osteoporesis in my hips at age 40.Drugs and even calcuim was not helping. When to bone specialist. my Vitamin D level was fine but after doing a 24hour urine collection , it was found that I was excreted most of my calcuim thru my urine. They placed me on Dyazide(water pill) and tested my urine the next year again and I wasnt excreting hardly any caluim (Was ecxcreting 250mg comparedd to 1400mg).
So good luck – I,too,refused taking fosamax,etc – took Fosamax for 7 years – bone density got worse. Now I am stable
Thank you,Vivian, for the useful info on Prolia but why is it that big pharma only deals with preserving old bone? It seems more logical to me to boost the bone building matrix so that you get more new bone forming. Am I overlooking something?
Best wishes
Marion
You can get it here: https://saveourbones.com/program/
Nope… you’re absolutely correct, Marion!
My doctor recently talked about a ‘new’ drug coming to market. She was a little put out that I had stopped Alendronate (however, I feel better than I have in the 10 years I took that drug). After reading this article, I have serious doubts about consenting to take it.
I do like your program, Vivian. Thanks from all of us out here who have been told we are ‘in trouble’! Are we, really?