This month's bulletin begins with a hot topic in the technology world: artificial intelligence, or AI. A new study suggests that a novel deep neural network may help identify osteoporosis risk earlier and more accurately than current methods.

Next, we’ll explore research on the relationship between osteoporosis and a DNA lifespan marker known as telomeres. Shortening of telomeres has been associated with numerous chronic health conditions.

Finally, you'll learn about how doctors who judge their patients for repeating health misinformation may be putting them at risk. An open and honest relationship with your doctor is critical, and this study identifies a major obstacle.

AI Model Applied To Osteoporosis Detection

A June 2024 study published in Frontiers in Artificial Intelligence reported the development of a novel deep neural network (DNN) model– a type of artificial intelligence (AI) program– that proved effective at early diagnosis of osteoporosis.

The researchers aimed to improve the diagnosis and treatment of osteoporosis, particularly in older adults. Previous efforts to use computer models for diagnosing osteoporosis faced computational challenges that hindered accuracy.

Relevant Excerpt

“The new DNN model overcomes these issues by using advanced techniques to analyse large and diverse data sets. This results in higher accuracy and better identification of at-risk patients, making it a more reliable tool for early diagnosis and treatment, ultimately improving patient care.

The researchers utilized a comprehensive dataset to develop their DNN model, incorporating diverse patient demographics and clinical variables. By training the model on this extensive dataset, they aimed to create an algorithm capable of accurately predicting osteoporosis risk and identifying patients who would benefit from early intervention.”¹

This new diagnostic tool could help doctors alert patients to an increased risk of bone loss and fracture. Like other diagnostic tools that have been developed for osteoporosis, this one could easily be leveraged by Big Pharma to drive an increase in prescriptions.

However, early detection could be an opportunity for doctors to recommend exercise, diet, and lifestyle interventions, like those advised by the Osteoporosis Reversal Program.

Synopsis

A new study reports the development of an artificial intelligence program called a novel deep neural network model that proved effective at early diagnosis of osteoporosis. This tool could facilitate earlier interventions to prevent bone loss and fracture.

Osteoporosis Linked To Telomere Shortening

A recent study published in the journal Aging found that leukocyte telomere length (LTL) decreased more quickly in participants with osteoporosis than those without.

Telomeres are protein and DNA structures found at the ends of chromosomes that protect the ends of DNA and control a cell's lifespan. Shortened telomere length is linked to various age-related chronic conditions.

Relevant Excerpt

“A total of 233 subjects (from 55 to 88 years) from the KBASE cohort were finally enrolled in the study. We observed that the LTL decreased by approximately 1.2 kbp over 2 years. While the LTL decreased as age increased, the rate of LTL shortening did not increase with age. Multivariable linear regression analysis indicated that only osteoporosis was independently associated with rapid LTL shortening over 2 years.

We sought to identify an association between osteoporosis and LTL shortening in an independent prospective cohort. We found that participants with osteoporosis had significantly faster LTL shortening over 2 years than those without osteoporosis.”²

This study didn't investigate the mechanism behind this association. However, it clearly demonstrates the interconnectedness of our bodily systems.

Preventing and reversing osteoporosis could have broader positive effects on aging if it helps slow telomere shortening. Further study is required to understand the relationship and how it could impact the future of osteoporosis interventions.

Synopsis

A study found that leukocyte telomere length (LTL) decreased more quickly in participants with osteoporosis than in those without. Telomere shortening is associated with a number of age-related chronic conditions. More study is required to understand the mechanism behind the association.

Judgemental Doctors May Undermine Patients' Health

A study published in The Society For Medical Decision Making found that doctors and patients alike harbor negative judgments of people who share incorrect medical information or beliefs.

The researchers surveyed over 350 patients and 200 physicians. The survey presented participants with scenarios of patients sharing various health beliefs, ranging from accurate information to common misconceptions to conspiracy theories.

People and healthcare professionals both viewed patients more negatively as their expressed beliefs became more unreasonable .

Relevant Excerpt

“This finding is particularly concerning given that surveys show the majority of people hold at least some incorrect health-related beliefs. Common misconceptions, like thinking vitamin C cures colds or that eating sugar directly causes diabetes, are widespread. Yet, the study suggests that sharing these beliefs—even when they’re reasonable for a non-expert to hold—could lead to negative judgments from healthcare providers.

The implications of this study are far-reaching. If patients fear being judged for their beliefs, they may withhold crucial information from their doctors. This reluctance to share could lead to misdiagnosis, ineffective treatments, or missed opportunities for education and correction of misinformation.”²

The authors suggest that additional education or training for medical professionals may be needed to address this issue. However, this leaves patients in a difficult position. The only apparent solution is finding a doctor who does not judge his or her patients and who welcomes a two-way dialogue about health and intervention planning.

The Save Institute recommends finding a doctor who you feel comfortable communicating openly with, and who supports your pursuit of a drug-free intervention to improve bone strength and quality.

Synopsis

A survey of physicians and patients found that both groups had a negative judgment of patients who shared incorrect medical information or opinions. The study authors suggest thatpatients worried for being judged for sharing information may compromise their healthcare. An open, honest, and judgment-free line of communication with your doctors is imperative for receiving effective care.

What This Means To You

A positive relationship with your doctor is foundational for getting quality healthcare. Building that relationship can be easier and more successful if you have a plan.

The Osteoporosis Reversal Program has an entire section dedicated to helping Savers cultivate a healthy and supportive relationship with their healthcare provider. The Doctor Communication Tutorials provide useful tools, like breakdowns of the five doctor personality profiles and how to best communicate with each type.

With new tools like AI entering healthcare and new research published each month, there are abundant opportunities to learn about breakthroughs and new strategies to keep your bones healthy and strong.

References

¹ https://www.pharmaceutical-technology.com/analyst-comment/osteoporosis-ai-model-diagnosis/?cf-view

² https://www.aging-us.com/article/206034/text

³ https://studyfinds.org/the-doctors-office-where-honesty-isnt-always-the-best-policy/