Today’s Save Our Bones Bulletin reveals a new twist on the same old osteoporosis drug story – the latest drug is in its Phase 3 trials. Basically, it’s an existing (and dangerous) drug in a new package.
Also, a brand new kind of osteoporosis drug is in the works, and believe it or not, it contains a chemical that has been shown to increase the growth of malignant breast tumors. Really scary!
And we end with a happy note, because there’s hopeful news out of Canada: a British Columbia city is removing fluoride from its municipal water systems.
Read on to find out more!
1. Abaloparatide Patch In Phase 3 Trial
Pharmaceutical company Radius announces Phase 3 trials of an osteoporosis drug called abaloparatide. One form is delivered via skin patch, and the other is a self-administered injection.
Radius’ investigational drug abaloparatide is a synthetic peptide analog of human parathyroid hormone-related protein (hPTHrP), a naturally occurring bone-building hormone that we believe has the potential to increase bone mineral density by stimulating new bone formation. Abaloparatide-SC is an investigational drug currently in Phase 3 development for potential use as a daily self-administered injection for the treatment of patients with postmenopausal osteoporosis at high risk of fracture. Radius also is developing the investigational drug abaloparatide-TD for potential use as a short wear-time transdermal patch designed to administer abaloparatide without the need for subcutaneous injection based on 3M's patented Microstructured Transdermal System technology.” 1
Savers surely know that this is nothing new. Despite the report’s glowing language, abaloparatide is similar to teriparatide, currently known as Forteo, which is already given as a subcutaneous (under the skin) injection.
Abaloparatide therefore will most likely carry all the dangerous side effects of Forteo, such as an increased risk of a rare bone cancer called osteosarcoma.
Teriparatide is shrouded in mystery; how it “works” still remains unknown, but this doesn’t seem to deter Big Pharma. Frankly, I cannot imagine risking cancer in order to avoid a fracture…especially when there are safe, drug-free options for reducing fracture risk.
2. A New Kind Of Osteoporosis Drug Uses Dangerous Synthetic Hormones
When I read stories like this one, I can’t help but shake my head. Big Pharma is trying once again to come up with the “perfect” osteoporosis drug, this time by manipulating bone metabolism via hormone-derived peptides.
Alizé Pharma III SAS, an Alizé Pharma group company…today announces that it has acquired exclusive worldwide rights to develop and commercialize a new family of peptides with bone anabolic properties.
The peptides are derived from a fragment of a physiological protein, called IGFBP-2 (Insulin-like Growth Factor Binding Protein-2). In vitro and in vivo studies showed the peptides’ ability to induce bone formation by stimulating osteoblast differentiation and inhibiting osteoclast differentiation.
This new and unique mechanism of action supports the development of a new therapeutic approach for the treatment of osteoporosis…” 2
Savers are familiar with insulin-like growth factor (IGF-1) – it’s found in cow’s milk as a result of cows being given injections of bovine growth hormone.
Even more disturbing, a 2004 study specifically cites IGFBP-2 as causing breast cancer growth, and shows that it is indicative of malignancy:
IGFBP2 mitogenic signals of autocrine/paracrine regulatory mechanisms may be responsible for the growth of breast carcinomas and IGFBP2 may be an independent indicator of malignancy.” 3
Of all the reasons not to take osteoporosis drugs, I think avoiding the risk of breast cancer is one of the most significant ones.
You see, the Medical Establishment and Big Pharma have the wrong approach. They are trying to develop more drugs because they believe osteoporosis is a disease, and therefore, it can only be “cured” with drugs.
As explained in Chapter 1 of the Osteoporosis Reversal Program, osteoporosis is not a disease. This is part of the Medical Establishment’s ploy to scare you and get you to take osteoporosis drugs. As Savers know, osteoporosis is symptomatic of an imbalance in the body that can correct itself if the conditions that caused the imbalance are corrected.
This does not require drugs. The drug-free Save Our Bones approach involves developing your unique bone health philosophy and supporting your body to achieve systemic balance.
Let’s remember that drugs don’t cure diseases; they only mask symptoms. And regardless of the drug’s purported effect(s), all drugs carry the risk of side effects, some of them unfortunately quite serious.
3. Canadian City Removes Fluoride From Public Water Supplies
This is really good news! Since 1954, City of Prince George has had fluoride in its municipal water. Now, the city has given itself a Christmas present: fluoride-free tap water.
As of December 31, the City of Prince George, British Columbia, Canada will be fluoride-free for the first time since October 4, 1954 – finally escaping from municipal water fluoridation toxicity in 60 years.
A vote to end fluoridation took place in November of this year, and it was unanimously accepted by the new Mayor and Council, expressing the wishes of Prince George residents.
The unanimous decision to end fluoridation comes with the dismantling and removal of all fluoridation equipment and hazardous waste storage tanks. This also means that as a province, British Columbia is now close to 98% FLUORIDE FREE – by choice.” 4
I like to think that the truth is unstoppable, and this story proves it. Hopefully, it will be the first of many like it in the near future, as the truth about fluoride continues to spread across the world.
There Is No Substitute For Knowledge And Information
Big Pharma and the Medical Establishment rake in big profits by keeping you in the dark. The same is true for the Establishment in general, as in the case of adding fluoride to drinking water under the premise of “better dental health.”
But if you gather unbiased, scientifically-based knowledge, you will find out the truth. Fluoride in drinking water is a perfect example.
Fluoridated compounds, including sodium fluoride, have been used as the active ingredient for pest control since the end of the nineteenth century, mainly against cockroaches, ants, and rats. This is why in the United States, toothpaste with fluoride carries a warning label (surprisingly only) since April 1997. Additionally, as many as 150 herbicides contain fluoride, and few know that non-stick coatings, such as Teflon™, are made of fluoride…”
In The Missing Link, you’ll also learn how water fluoridation began as a collaboration between biochemist Gerald J. Cox, the Aluminum Company of America, and fertilizer producers that needed somewhere to dump their toxic fluoride by-products.
And let’s not forget how bad fluoride is for your bones, in part because it has been shown to damage the thyroid, which plays a significant role in bone metabolism.
There are many studies showing that fluoride increases fracture risk (particularly hip fractures). Beginning in the 1980s, study after study (many of which are listed in The Missing Link), showed that drinking fluoridated water increased hip fracture risk.
Learning The Truth Allows You To Take Control Of Your Own Bone Health
This is why the Medical Establishment does not like for the population to search for answers, and often demonizes “alternative” approaches as ignorant – when in fact the opposite is true.
The bottom line is, osteoporosis is a condition that can easily be reversed through pH-balanced nutrition, implementing simple lifestyle changes (even something as simple as not drinking fluoridated tap water), and engaging in regular, targeted exercise.
Save Our Bones is all about understanding the “big picture” and explaining the details necessary for implementing this view. And that is the winning combination that makes a huge difference in rejuvenating your bones.
1 “Radius Announces Positive Phase 3 Top-Line Results for Its Investigational Drug Abaloparatiide-SC in Postmenopausal Women With Severe Osteoporosis.” Global News Wire. December 21, 2014. Web. http://www.globenewswire.com/news-release/2014/12/22/693147/10113202/en/Radius-Announces-Positive-Phase-3-Top-Line-Results-for-Its-Investigational-Drug-Abaloparatide-SC-in-Postmenopausal-Women-With-Severe-Osteoporosis.html
2 “Alizé Pharma obtains exclusive worldwide rights to develop new therapy for bone diseases.” News Medical. December 4, 2014. Web. http://www.news-medical.net/news/20141204/Alize-Pharma-obtains-exclusive-worldwide-rights-to-develop-new-therapy-for-bone-diseases.aspx
3 Busund, L.T., et al. “Significant expression of IGFBP2 in breast cancer compared with benign lesions.” J Clin Pathol. 2005. 58:361-366. Web. http://jcp.bmj.com/content/58/4/361
4 Sarich, Christina. “City Goes Fluoride-Free For Christmas: Overturning a 60-Year Public Health Hazard Law.” Natural Society. December 17, 2014. Web. http://naturalsociety.com/city-goes-fluoride-free-christmas/