This month’s Bulletin covers new research that shows once again how ineffective and dangerous osteoporosis drugs are. This time the daily injectable drug Forteo (teriparatide) is on the stand, facing evidence that its already detrimental effects on bones are further confirmed by the chaos it wreaks on the bone remodeling process after ending treatment.
Then we bring you good news about the eating habits of Americans and the British. The consumption of animal protein is down in both countries, marking a positive trend in nutritionally sound choices. We’ll look at the figures and see how the Save Institute’s recommendations fit right into this bi-continental rejection of unhealthy habits.
Last, you’ll get an update on a peptide that has been proposed as a potential new osteoporosis drug. The already crowded field of dangerous and ineffective drugs may be welcoming a new member. We’ll look at the study in question and consider what this means for Big Pharma and for those who are diagnosed with osteoporosis and osteopenia.
Study Shows Forteo Is Ineffective
New research has been published about the negative impacts of treatment with teriparatide, the generic name for the osteoporosis drug Forteo.
Teriparatide is a recombinant form of parathyroid hormone, essentially a laboratory produced equivalent of the endogenous substance, which by an unknown mechanism seems to stimulate the production of osteoblasts and increases their lifespan. Osteoblasts are the cells that are involved in bone deposition.
The purpose of the drug is to increase bone density by causing osteoblasts to ramp up bone production. While there are plenty of problems with this as a way to prevent fracture (starting with its ineffectiveness) this new study reveals that the drug creates even more problems after treatment is ended.
“A study published this week in the JCI reports that the number of osteoblast precursor cells and their mature descendants increased in mice undergoing teriparatide treatment. When mice were withdrawn from teriparatide treatment, not only did osteoblast proliferation diminish, but the number of newly-formed fat cells, or adipocytes, increased… The findings also offer insights into possible drawbacks of teriparatide therapy, indicating that the long-term consequences of brief treatment periods could outweigh the benefits.”1
This last line is particularly troubling, especially as it refers to a drug that many people were unwittingly talked into taking, and that has been shown to cause bone cancer (osteosarcoma) in laboratory rats, among other undesirable side effects.2 The newly discovered study results, which showed that cessation of treatment with Forteo causes an increase in fat cells and the degradation of the bone-building process, is clear proof that it does not address the root cause of bone loss (just like the rest of the osteoporosis drugs). This is the exact opposite of the Osteoporosis Reversal Program, which addresses the underlying causes of bone loss and provides a safe and natural means of improving bone quality and tensile strength.
Meat Consumption Is Down In US and UK
Two studies have shown that meat consumption is down in both the United States and Great Britain.
Americans have cut back a small measure on pork and poultry, but the most encouraging news for the nation’s health is the reduction in (acidifying) beef consumption. The findings were reported in The New York Times.
“The last decade or so has brought ample evidence that Americans are gradually changing their diets, driven by health concerns and other factors.
But a new study points to one change that is starker than many have thought: Americans cut their beef consumption by 19 percent — nearly one-fifth — in the years from 2005 to 2014, according to research released on Wednesday by the Natural Resources Defense Council.
The environmental group found that consumption of chicken and pork fell as well, though less drastically, as Americans ate more cheese, butter and leafy greens. The council is hailing the plummeting popularity of beef as a victory in the fight against climate change, because greenhouse gases are produced when cattle are raised.”3
The British are experiencing a similar trend. A report published by an organization that advocates for vegetarian or reduced meat diets has found that many Brits who normally eat meat have been cutting back on animal protein.
“Meat-Free Foods 2017, a report produced by market research company Mintel, reveals that 28% of British omnivores have cut back on the amount of meat they eat over the past six months. Another 14% said they would be interested in doing so in the future.
And the report confirms that Meat Free Monday has played a significant part in opening people’s eyes to the delights of meat free food, as well as to the dangers and downsides of meat-eating.
While just under half (49%) of those who are curbing their meat intake or were interested in doing so said it was for health reasons – followed by weight-loss (29%) and the environment joint third with animal welfare on 24% – it’s reassuring to see young people leading the way in terms of green eating. Sounding a positive note for the future of the planet, almost a third (29%) of meat-reducers under the age of 25 said their dietary choice was a climate-conscious one.”4
Both of the articles mention the positive environmental impact of eating less meat.
Whether they realize it or not, those who reported eating less meat and more leafy greens were more likely to achieve a more balanced pH, which is critical for bone health and overall health.
Meat is and acidifying food. When acidifying foods make up more than about 20% of your diet, your body’s pH is thrown off. To rectify this imbalance, your body strips your bones of alkalizing minerals, such as calcium and magnesium. This weakens your bones, reducing their tensile strength, and leaving them susceptible to fracture.
By eating plenty of alkalizing foods, you’ll prevent this process, while simultaneously providing your body with the nutrients it needs to stay healthy and strong. The trend of eating less meat is one worth joining. Your bones with thank you!
New Drug In The Works
A new study published in the medical journal Cell Death and Differentiation has identified a potential new osteoporosis drug. Researchers led by Seoul National University School of Dentistry professor Min Byung-moo have isolated a vitronectin-derived peptide shown to reverse ovariectomy-induced bone loss in mice, via regulation of osteoblast and osteoclast differentiation.
“A functional peptide substance in “vitronectin,” a type of protein commonly found in serum and bone tissues, was found to facilitate the differentiation of osteoblasts that synthesize bones, stimulating the cells to form bones while hindering osteoclasts from breaking down bone tissues.
When the research team injected this substance into a rat whose ovary had been removed, the number of osteoblasts in its bones increased. This hints at a possibility that the functional peptide substance can be useful in the treatment of osteoporosis, especially for elderly women with the disease given that around 30 percent of postmenopausal women develop osteoporosis due to decreased ovarian production of hormones.”5
The Medical Establishment’s fixation on quick-fix pharmaceutical solutions has lead to a string of ineffective and dangerous drugs that are marketed to turn a profit for their Big Pharma creators. The drug that may emerge from vitronectin will likely be no different.
Stop Worrying About Your Bone Loss
Join thousands of Savers from around the world who have reversed or prevented their bone loss naturally and scientifically with the Osteoporosis Reversal Program.
Research has already shown that what the body needs to create stronger, more resilient bones is not a side-effect-ridden osteoporosis drug but rather, proper nutrition, a bone-smart lifestyle, and plenty of exercise. The Osteoporosis Reversal Program applies that science-based knowledge to craft an approach bone quality improvement and fracture risk reduction that is both absolutely safe and proven effective.
Till next time,
1 JCI Journals. “A closer look at osteoporosis medications’ mechanisms may improve outcomes: Teriparatide therapy increases production of bone-forming cells, but ending treatment may lead to unwanted effects.” ScienceDaily.ScienceDaily, 31 July 2017. www.sciencedaily.com/releases/2017/07/170731164429.htm.
3 Stephanie Strom. “Americans Ate 19% Less Beef From ’05 to ’14, Report Says.” The New York Times. March 21, 2017. Web: https://www.nytimes.com/2017/03/21/dining/beef-consumption-emissions.html?mcubz=1
4 Meat Free Mondays. August 14, 2017. Web: https://www.meatfreemondays.com/quarter-brits-eating-less-meat/
5 “Possible cure for chronic osteoporosis found.” THE DONG-A ILBO. November. 13, 2017. Web: https://english.donga.com/List/3/08/26/1125368/1